Monday, February 10, 2014

The Longevity Paradox: Why Living To 100 is Easier For Some People Than Living to 85 is For Most

Do you want to know what the absolute truths about longevity are? Truths that are irrefutable? Truths that if followed will always produce the same desired results? 

If you are reading this expecting me to provide you with such truths, let me apologize in advance. I have searched for them for the past three years by speaking to over 1,000 senior citizens, several over 100, in reading over 50 books, 35,000 studies/abstracts and countless online articles, and I am sorry to say that they don't appear to exist. With titles like Blue Zones, The Longevity Project, Successful Aging, The Art of Living Long, etc., I just can’t find any consistent and foolproof science-based advice. I’ve studied the published material from the Okinawa, New England, and Albert Einstein College of Medicine Centenarian studies, read publications from the SENS Research Foundation and available proceedings from International Longevity conferences. It just can't find it.

The reason there doesn’t seem to be any absolute right answer is because when it comes to longevity there appears to be a paradox.
 
Take smoking for example. There can hardly be a question regarding the association of cigarette smoking with lung cancer. Cigarettes can be considered dangerous producing debilitating lung diseases, which can sometimes—but not always--be lethal. Not every cigarette smoker develops lung cancer, and for that matter, not every lung cancer patient previously smoked or was exposed to second-hand fumes.   

In Daniel Buetner's book Blue Zones, he reveals five places, such as Sardinia, Italy and Nicoya, Costa Rica, scattered around the globe that harbor relatively high concentrations of centenarians, people aged over 100. He ascribes their longevity to living a certain healthy lifestyle. It often comes down to the food they eat, the physical activity they do, their attitude towards life and family, etc.  However, in these same areas there are plenty of friends, family, and neighbors who lived remarkably similar lives and yet met much early demises. Not surprisingly, in searching out the life expectancy for these ‘Blue Zone’ areas, I found that they are for the most part only slightly higher than life expectancies in other parts of the world with far fewer centenarians. 

Yet, books and articles continue to get published offering the ‘secrets’ and ‘keys’ to living to 100 if you follow a few similar rules such as eating properly, exercising, sleeping enough, managing stress, being social, etc. But do these actions always matter? Unfortunately, the answer today appears to be no. Commonsense and plenty of supporting science affirms the notion that certain lifestyle activities, such as a sedentary life and poor eating habits may lead to premature chronic diseases such as diabetes, heart disease and cancer. But, ‘may’ is not always. 

To prove my point, let me share my own recently completed informal, admittedly unscientific, but revealing research project. The project involved accumulating all the stories about centenarians published online in 2013. Most of the stories were identified through a Google alert email for the keyword "longevity." After identifying over 50 stories, I searched each story for the centenarians' 'secret' or 'key' to longevity. I created a chart of the first 50 individuals I randomly came across that offered a revelation.

Here are the results.  

The oldest centenarian was 114, with many having turned 100 just last year. 35 were women and 15 were men.

Here are the reasons (totaled for times cited with overlap so adds up to more than 50) they gave for their longevity: 

18 attribute it to (hard) work and physical activity
10 attribute it to regular alcohol consumption

6 attribute it to strictly never drinking or smoking


14 attribute it to a good attitude towards life and/or to faith








1 to Anacin pills











1 to love of roller coasters










1 to good doctors










1 to cafe lattes (long before they became popular)










1 to marrying a man thirty years younger








1 to eating bacon











1 to eating Italian food










1 to eating junk food










1 credited  cigarettes and 1 credited cigars (and yet, no lung cancer)










2 claimed no explanation











Since I put this chart together, I came across four more stories in January 2014 for 100, 104, 108 and 109 year olds. The 100 year old claimed his longevity was due to eating lots of strawberry ice cream, just like his father did, who lived to 104. The 104 year old credited her longevity to her love of eating chocolate and drinking hot chocolate.  The 108 year old stated that it was in part due to never marrying and avoiding the accompanying decades of stress. The 109 gave her key to longevity as not eating a lot and never between meals.




Now as you review this list, it should be clear that there were no absolute reliable and consistent reasons as to why any of them lived past 100. In fact, scientists at Albert Einstein College of Medicine and at Boston University, who have been studying centenarians for many years, concur that there is no single absolute explanation for centenarian longevity. The current thinking is these longevity winners possess a number of small genetic variations that work together as a group to confer benefit to them. According to Thomas Perls, a Boston University professor of medicine and director of the New England Centenarian Study, "Twenty percent of the population has the genetic wherewithal to get to be 100."




















So what does that mean for the eighty percent that represent the rest of us who may not enjoy such gene variations? Should we even bother to engage in a healthy lifestyle if there are no guarantees or absolutes? Why deny ourselves that piece of chocolate cake or bother to get out of our chairs and move at all if good health and longevity simply come down to winning the gene lottery?





























































The answer is that even though there are no absolutes when it comes to your health, there are probabilities and possibilities.




























































A healthy lifestyle increases the probability of a healthy life even as the possibility for poor health, like the inexplicable cancer, still exists. An unhealthy lifestyle increases the probability for poor health like heart disease and cancer, even though the possibility does exist that you will escape such devastating illnesses and still live to 100 like the few who did in the review cited above. On this point, the preponderance of scientific evidence is clear, although not absolute. For me it all comes down to what Louis Pasteur once said, which is that "Chance favors the prepared mind." In other words, sometimes we make our own luck. That's what I always told my patients.





























































So the next time you read an article claiming that one thing or another is the absolute way to good health and extended longevity or books like Grain Brain or Wheat Belly that claim that certain foods are absolutely bad for you, you should realize that such absolutes simply don't exist (although I can't only say that with absolute certainty). 






























































So beware of people claiming they have absolute answers for you. They can't be certain; no one can today, although the future may tell a different story.






























































The old adage that one man's poison may be another man's food, may come to mind. What works for one, may not work for another. You may still live to 100 by eating junk food, smoking, and never exercising. You won’t be the first and probably not the last. You could also win the next Powerball lottery. But if I were you, I wouldn't place all my bets on it. Especially, when it's your life and health at stake.

That's a lesson (almost) absolutely worth learning.